ATG10, autophagy related 10

ATG10, autophagy related 10

• Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (ubiquitin-like-conjugating enzyme ATG10, APG10 autophagy 10-like, ATG10 autophagy related 10 homolog, autophagy-related protein 10, APG10, APG10L, pp12616,)
• NCBI Gene ID: 83734
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H0Y0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

autophagy related 10 interacts with:

• immunity related GTPase M
  interferon lambda 2

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