KDM2B, lysine demethylase 2B

KDM2B, lysine demethylase 2B

• This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (lysine-specific demethylase 2B, CXXC-type zinc finger protein 2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein, [Histone-H3]-lysine-36 demethylase 1B, jmjC domain-containing histone demethylation protein 1B, jumonji C domain-containing histone demethylase 1B, lysine (K)-specific demethylase 2B, protein-containing CXXC domain 2, CXXC2, FBXL10, Fbl10, JHDM1B, PCCX2,)
• NCBI Gene ID: 84678
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DSN4
  UNIPROT ID#>>Q8NHM5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysine demethylase 2B interacts with:

• lysine demethylase 2B
  polycomb group ring finger 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.