RGS20, regulator of G protein signaling 20

RGS20, regulator of G protein signaling 20

• The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

• Gene Synonyms (regulator of G-protein signaling 20, gz-selective GTPase-activating protein, regulator of G-protein signaling 20 variant 2, regulator of G-protein signaling Z1, regulator of G-protein signalling 20, regulator of Gz-selective protein signaling 1, RGSZ1, ZGAP1, g(z)GAP, gz-GAP,)
• NCBI Gene ID: 8601
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KSW4
  UNIPROT ID#>>O76081
  UNIPROT ID#>>H9NIM5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

regulator of G protein signaling 20 interacts with:

• abhydrolase domain containing 17A, depalmitoylase
  alanyl-tRNA synthetase domain containing 1
  bolA family member 1
  cAMP responsive element binding protein 5
  cation channel sperm associated 1
  cysteine rich C-terminal 1
  cytokine induced apoptosis inhibitor 1
  cytosolic iron-sulfur assembly component 3
  cytosolic thiouridylase subunit 2
  DDB1 and CUL4 associated factor 10
  EFR3 homolog A
  EFR3 homolog B
  family with sequence similarity 126 member A
  Fas associated factor family member 2
  glutaredoxin 3
  homeobox A1
  kelch like family member 38
  keratin associated protein 4-2
  keratin associated protein 5-11
  keratin associated protein 5-6
  keratin associated protein 9-3
  keratin associated protein 9-8
  kinesin family member 3A
  kinesin family member 3B
  late cornified envelope 1A
  late cornified envelope 1B
  late cornified envelope 1F
  late cornified envelope 2A
  late cornified envelope 2B
  late cornified envelope 2C
  late cornified envelope 2D
  late cornified envelope 3A
  late cornified envelope 3C
  late cornified envelope 3D
  late cornified envelope 3E
  late cornified envelope 4A
  late cornified envelope 5A
  ligand of numb-protein X 1
  meiosis regulator for oocyte development
  mitogen-activated protein kinase binding protein 1
  molybdenum cofactor sulfurase
  nectin cell adhesion molecule 3
  neurolysin
  NIMA related kinase 8
  nuclear FMR1 interacting protein 2
  nuclear prelamin A recognition factor
  osteoclastogenesis associated transmembrane protein 1
  phosphoglycolate phosphatase
  phosphomevalonate kinase
  protein tyrosine phosphatase mitochondrial 1
  RAD50 double strand break repair protein
  regulator of G protein signaling 19
  RuvB like AAA ATPase 2
  selenoprotein O
  serine palmitoyltransferase long chain base subunit 1
  stathmin 2
  taxilin alpha
  taxilin gamma
  TBC1 domain family member 16
  tetratricopeptide repeat domain 7B
  tRNA methyltransferase 1 like
  tRNA methyltransferase subunit 11-2
  tRNA-yW synthesizing protein 1 homolog
  vasorin
  zinc finger protein 444
  zinc finger protein 664
  zinc finger protein 696
  zyg-11 family member B, cell cycle regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.