PLPP3, phospholipid phosphatase 3

PLPP3, phospholipid phosphatase 3

• The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. [provided by RefSeq, Mar 2010]

• Gene Synonyms (phospholipid phosphatase 3, PAP2 beta, lipid phosphate phosphohydrolase 3, phosphatidate phosphohydrolase type 2b, phosphatidic acid phosphatase type 2B, type-2 phosphatidic acid phosphatase-beta, vascular endothelial growth factor and type I collagen inducible, Dri42, LPP3, PAP2B, PPAP2B, VCIP,)
• NCBI Gene ID: 8613
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14495
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipid phosphatase 3 interacts with:

• BCAR1 scaffold protein, Cas family member
  phospholipid phosphatase 3

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