TNFSF13, TNF superfamily member 13

TNFSF13, TNF superfamily member 13

• The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

• Gene Synonyms (tumor necrosis factor ligand superfamily member 13, TNF- and APOL-related leukocyte expressed ligand 2, a proliferation-inducing ligand, tumor necrosis factor (ligand) superfamily, member 13, tumor necrosis factor ligand 7B, tumor necrosis factor superfamily member 13, tumor necrosis factor-like protein ZTNF2, tumor necrosis factor-related death ligand-1, APRIL, CD256, TALL-2, TALL2, TNLG7B, TRDL-1, UNQ383/PRO715, ZTNF2,)
• NCBI Gene ID: 8741
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75888
  UNIPROT ID#>>Q2QBA2
  UNIPROT ID#>>B3KR02
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TNF superfamily member 13 interacts with:

• calcium/calmodulin dependent protein kinase ID
  small glutamine rich tetratricopeptide repeat containing beta
  TNF receptor superfamily member 13B
  TNF receptor superfamily member 14
  TNF superfamily member 13
  TNF superfamily member 13b

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