LRSAM1, leucine rich repeat and sterile alpha motif containing 1

LRSAM1, leucine rich repeat and sterile alpha motif containing 1

• This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jan 2012]

• Gene Synonyms (E3 ubiquitin-protein ligase LRSAM1, RING finger leucine repeat rich, RING-type E3 ubiquitin transferase LRSAM1, Tsg101-associated ligase, CMT2P, RIFLE, TAL,)
• NCBI Gene ID: 90678
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R870
  UNIPROT ID#>>Q6UWE0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

leucine rich repeat and sterile alpha motif containing 1 interacts with:

• leucine rich repeat and sterile alpha motif containing 1
  tripartite motif containing 74

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.