PKMYT1, protein kinase, membrane associated tyrosine/threonine 1

PKMYT1, protein kinase, membrane associated tyrosine/threonine 1

• This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

• Gene Synonyms (membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, myt1 kinase, protein phosphatase 1, regulatory subunit 126, MYT1, PPP1R126,)
• NCBI Gene ID: 9088
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q0IJ49
  UNIPROT ID#>>Q99640
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein kinase, membrane associated tyrosine/threonine 1 interacts with:

• cyclin B2
  cyclin-dependent kinase 1
  fetal and adult testis expressed 1
  Lck interacting transmembrane adaptor 1
  leucine rich repeat containing 25
  major facilitator superfamily domain containing 14B
  major facilitator superfamily domain containing 5
  OTU deubiquitinase with linear linkage specificity like
  perilipin 3
  reticulophagy regulator family member 3
  rhomboid domain containing 1
  serine peptidase inhibitor, Kunitz type 2
  solute carrier family 30 member 8
  STEAP3 metalloreductase
  thioredoxin related transmembrane protein 2
  THO complex 2
  transmembrane protein 101
  transmembrane protein 216
  transmembrane protein 229B
  tubulin, gamma 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.