LPAR2, lysophosphatidic acid receptor 2

LPAR2, lysophosphatidic acid receptor 2

• This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (lysophosphatidic acid receptor 2, G protein-coupled receptor, LPA receptor 2, LPA receptor EDG4, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4, lysophosphatidic acid receptor EDG4, lysophosphatidic acid receptor Edg-4, EDG-4, EDG4, LPA-2, LPA2,)
• NCBI Gene ID: 9170
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R7M9
  UNIPROT ID#>>Q9HBW0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysophosphatidic acid receptor 2 interacts with:

• GIPC PDZ domain containing family member 1
  Rho guanine nucleotide exchange factor 11
  Rho guanine nucleotide exchange factor 12
  SIVA1 apoptosis inducing factor
  SLC9A3 regulator 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.