GPR50, G protein-coupled receptor 50

GPR50, G protein-coupled receptor 50

• This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]

• Gene Synonyms (melatonin-related receptor, H9, Mel1c,)
• NCBI Gene ID: 9248
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13585
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein-coupled receptor 50 interacts with:

• adhesion G protein-coupled receptor G5
  clusterin associated protein 1
  C-type lectin domain family 2 member D
  G protein-coupled receptor 50
  inositol-pentakisphosphate 2-kinase
  transmembrane protein 171
  zinc finger protein 572

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.