MARCHF9, membrane associated ring-CH-type finger 9

MARCHF9, membrane associated ring-CH-type finger 9

• MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).[supplied by OMIM, Apr 2010]

• Gene Synonyms (E3 ubiquitin-protein ligase MARCHF9, E3 ubiquitin-protein ligase MARCH9, RING finger protein 179, RING-type E3 ubiquitin transferase MARCH9, RING-type E3 ubiquitin transferase MARCHF9, membrane associated ring finger 9, membrane-associated RING finger protein 9, membrane-associated RING-CH protein IX, membrane-associated ring finger (C3HC4) 9, MARCH-IX, MARCH9, RNF179,)
• NCBI Gene ID: 92979
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N9T1
  UNIPROT ID#>>Q86YJ5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

membrane associated ring-CH-type finger 9 interacts with:

• membrane associated ring-CH-type finger 9
  POTE ankyrin domain family member I

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