SRA1, steroid receptor RNA activator 1

SRA1, steroid receptor RNA activator 1

• Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA. [provided by RefSeq, Mar 2012]

• Gene Synonyms (steroid receptor RNA activator 1, steroid receptor RNA activator 1 (complexes with NCOA1), steroid receptor RNA activator protein, steroid receptor coactivator, SRA, SRAP, STRAA1, pp7684,)
• NCBI Gene ID: 10011
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HD15
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

steroid receptor RNA activator 1 interacts with:

• centrosomal protein 43
  DNA polymerase kappa
  excision repair cross-complementing rodent repair deficiency complementation group 6 like
  mindbomb E3 ubiquitin protein ligase 1
  mixed lineage kinase domain like pseudokinase
  RUN and FYVE domain containing 1
  spen family transcriptional repressor
  tigger transposable element derived 6
  ubiquitin conjugating enzyme E2 T
  ubiquitin conjugating enzyme E2 Z

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.