RAMP2, receptor activity modifying protein 2

RAMP2, receptor activity modifying protein 2

• The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq, Jul 2008]

• Gene Synonyms (receptor activity-modifying protein 2, CRLR activity-modifying protein 2, calcitonin receptor-like receptor activity modifying protein 2, receptor (G protein-coupled) activity modifying protein 2, receptor (calcitonin) activity modifying protein 2,)
• NCBI Gene ID: 10266
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60895
  UNIPROT ID#>>A0A024R1Z2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

receptor activity modifying protein 2 interacts with:

• cell death inducing DFFA like effector b

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