ABCA7, ATP binding cassette subfamily A member 7

ABCA7, ATP binding cassette subfamily A member 7

• The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ABCA-SSN, ABCX, AD9, phospholipid-transporting ATPase ABCA7, ATP-binding cassette sub-family A member 7, ATP-binding cassette, sub-family A (ABC1), member 7, autoantigen SS-N, macrophage ABC transporter,)
• NCBI Gene ID: 10347
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KUJ3
  UNIPROT ID#>>Q8IZY2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATP binding cassette subfamily A member 7 interacts with:

• HAUS augmin-like complex, subunit 1
  small glutamine rich tetratricopeptide repeat containing beta
  synaptotagmin binding cytoplasmic RNA interacting protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.