PEMT, phosphatidylethanolamine N-methyltransferase

PEMT, phosphatidylethanolamine N-methyltransferase

• Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]

• Gene Synonyms (PEAMT, PEMPT, PEMT2, PLMT, PNMT, phosphatidylethanolamine N-methyltransferase, phospholipid methyltransferase,)
• NCBI Gene ID: 10400
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UBM1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylethanolamine N-methyltransferase interacts with:

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