LRRN2, leucine rich repeat neuronal 2

LRRN2, leucine rich repeat neuronal 2

• The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (FIGLER7, GAC1, LRANK1, LRRN5, leucine-rich repeat neuronal protein 2, fibronectin type III, immunoglobulin and leucine rich repeat domain 7, glioma amplified on chromosome 1 protein, leucine rich and ankyrin repeats 1, leucine rich repeat neuronal 5, leucine-rich repeat neuronal protein 5,)
• NCBI Gene ID: 10446
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75325
  UNIPROT ID#>>A0A024R993
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

leucine rich repeat neuronal 2 interacts with:

• activating transcription factor 6
  DnaJ heat shock protein family (Hsp40) member C18
  ethanolamine kinase 1
  F-box protein 11
  LARGE xylosyl- and glucuronyltransferase 2
  leucine rich repeats and immunoglobulin like domains 3
  neuronal differentiation 4
  suppression of tumorigenicity 7 like
  ubiquitin specific peptidase 22

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.