SLCO1B1, solute carrier organic anion transporter family member 1B1

SLCO1B1, solute carrier organic anion transporter family member 1B1

• This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

• Gene Synonyms (HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6, solute carrier organic anion transporter family member 1B1, OATP-2, liver-specific organic anion transporter 1, sodium-independent organic anion-transporting polypeptide 2, solute carrier family 21 (organic anion transporter), member 6,)
• NCBI Gene ID: 10599
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RAU7
  UNIPROT ID#>>Q05CV5
  UNIPROT ID#>>Q9Y6L6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier organic anion transporter family member 1B1 interacts with:

• dymeclin
  mitotic spindle organizing protein 2B
  ORMDL sphingolipid biosynthesis regulator 2
  RAB5 interacting factor
  WAPL cohesin release factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.