CORIN, corin, serine peptidase

CORIN, corin, serine peptidase

• This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]

• Gene Synonyms (ATC2, CRN, Lrp4, PEE5, TMPRSS10, atrial natriuretic peptide-converting enzyme, heart-specific serine proteinase ATC2, pro-ANP-convertase, pro-ANP-converting enzyme, transmembrane protease serine 10,)
• NCBI Gene ID: 10699
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4E2W9
  UNIPROT ID#>>Q9Y5Q5
  UNIPROT ID#>>J3KR83
  UNIPROT ID#>>B4E1Y7
  UNIPROT ID#>>A0A087X1D5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

corin, serine peptidase interacts with:

• glutathione peroxidase 8 (putative)

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