GLIPR1, GLI pathogenesis related 1

GLIPR1, GLI pathogenesis related 1

• This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CRISP7, GLIPR, RTVP1, glioma pathogenesis-related protein 1, GLI pathogenesis-related 1 (glioma), gliPR 1, protein RTVP-1, related to testis-specific, vespid, and pathogenesis proteins 1, testes-specific vespid and pathogenesis protein 1,)
• NCBI Gene ID: 11010
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P48060
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

GLI pathogenesis related 1 interacts with:

• arachidonate lipoxygenase 3
  CKLF like MARVEL transmembrane domain containing 6
  double zinc ribbon and ankyrin repeat domains 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.