Srsf1, serine and arginine-rich splicing factor 1

Srsf1, serine and arginine-rich splicing factor 1

• The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

• (No alternate names found)
• NCBI Gene ID: 110809
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q6PDM2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine and arginine-rich splicing factor 1 interacts with:

• Fanconi anemia, complementation group D2
  heterogeneous nuclear ribonucleoprotein A3
  heterogeneous nuclear ribonucleoprotein A3
  RBMX like 1
  RNA binding motif protein 12B
  taxilin alpha
  tetratricopeptide repeat domain 14
  zinc finger protein 326

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.