ADAMTS13, ADAM metallopeptidase with thrombospondin type 1 motif 13

ADAMTS13, ADAM metallopeptidase with thrombospondin type 1 motif 13

• This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Gene Synonyms (A disintegrin and metalloproteinase with thrombospondin motifs 13, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13, vWF-cleaving protease, von Willebrand factor-cleaving protease, ADAM-TS13, ADAMTS-13, C9orf8, VWFCP, vWF-CP,)
• NCBI Gene ID: 11093
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q76LX8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ADAM metallopeptidase with thrombospondin type 1 motif 13 interacts with:

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