AKAP11, A-kinase anchoring protein 11

AKAP11, A-kinase anchoring protein 11

• The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]

• Gene Synonyms (A-kinase anchor protein 11, A kinase (PRKA) anchor protein 11, A-kinase anchor protein 220 kDa, A-kinase anchoring protein, 220kDa, a kinase anchor protein 220 kDa, protein kinase A anchoring protein 11, protein phosphatase 1, regulatory subunit 44, AKAP-11, AKAP220, PPP1R44, PRKA11,)
• NCBI Gene ID: 11215
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKA4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

A-kinase anchoring protein 11 interacts with:

• agrin
  cramped chromatin regulator homolog 1
  DNA cross-link repair 1C
  egl-9 family hypoxia inducible factor 3
  erythroblast membrane associated protein (Scianna blood group)
  family with sequence similarity 43 member A
  kelch like family member 28
  protein kinase, cAMP dependent, catalytic, beta
  SET and MYND domain containing 2
  transcription factor Dp family member 3
  tRNA methyltransferase 1
  vir like m6A methyltransferase associated
  VPS28 subunit of ESCRT-I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.