KLF8, Kruppel like factor 8

KLF8, Kruppel like factor 8

• This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

• Gene Synonyms (Krueppel-like factor 8, basic krueppel-like factor 3, basic kruppel-like factor 3, zinc finger protein 741, BKLF3, ZNF741,)
• NCBI Gene ID: 11279
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R9X4
  UNIPROT ID#>>O95600
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Kruppel like factor 8 interacts with:

• ANTXR cell adhesion molecule 1
  DGCR8 microprocessor complex subunit
  MICAL like 1
  small G protein signaling modulator 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.