ATP6V1G3, ATPase H+ transporting V1 subunit G3

ATP6V1G3, ATPase H+ transporting V1 subunit G3

• This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ATP6G3, Vma10, V-type proton ATPase subunit G 3, ATPase, H+ transporting, lysosomal (vacuolar proton pump) subunit G3, ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3, V-ATPase 13 kDa subunit 3, V-ATPase G subunit 3, V-ATPase G3 subunit, V-ATPase subunit G 3, vacuolar ATP synthase subunit G 3, vacuolar proton pump G subunit 3, vacuolar proton pump subunit G 3, vacuolar proton pump, subunit G3,)
• NCBI Gene ID: 127124
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96LB4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATPase H+ transporting V1 subunit G3 interacts with:

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