ACMSD, aminocarboxymuconate semialdehyde decarboxylase

ACMSD, aminocarboxymuconate semialdehyde decarboxylase

• The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004]

• Gene Synonyms (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, picolinate carboxylase,)
• NCBI Gene ID: 130013
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z681
  UNIPROT ID#>>Q8TDX5
  UNIPROT ID#>>Q6ZV40
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

aminocarboxymuconate semialdehyde decarboxylase interacts with:

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