Emd, emerin

Emd, emerin

• This gene is the founding member of the LEM (Lap2beta, Emerin, and Man1) domain gene family. It encodes an integral membrane protein of the inner nuclear membrane. This gene may be involved in transcriptional regulation and genomic organization. In humans, mutations in this gene cause a class of diseases called laminopathies, which includes Emery-Dreifuss muscular dystrophy (EDMD). [provided by RefSeq, Apr 2013]

• (No alternate names found)
• NCBI Gene ID: 13726
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>A2AM95
  UNIPROT ID#>>O08579
  UNIPROT ID#>>Q3THM8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

emerin interacts with:

• ataxin 1
  BAF nuclear assembly factor 1
  calponin 3, acidic
  dpy-30, histone methyltransferase complex regulatory subunit
  Fanconi anemia, complementation group D2
  heat shock protein 1A
  heparin binding growth factor
  heterogeneous nuclear ribonucleoprotein K
  heterogeneous nuclear ribonucleoprotein U
  histone deacetylase 3
  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
  lamin A
  LSM8 homolog, U6 small nuclear RNA associated
  myosin, heavy polypeptide 9, non-muscle
  POU domain, class 5, transcription factor 1
  proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
  SH3-domain GRB2-like 2
  Sjogren syndrome antigen B
  small nuclear ribonucleoprotein D1
  tripartite motif-containing 28
  tubulin, beta 5 class I
  tubulin, gamma complex associated protein 2
  tubulin, gamma complex associated protein 4
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
  WD and tetratricopeptide repeats 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.