MESP2, mesoderm posterior bHLH transcription factor 2

MESP2, mesoderm posterior bHLH transcription factor 2

• This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02). [provided by RefSeq, Oct 2008]

• Gene Synonyms (SCDO2, bHLHc6, mesoderm posterior protein 2, class C basic helix-loop-helix protein 6, mesoderm posterior 2 homolog, mesoderm posterior basic helix-loop-helix transcription factor 2,)
• NCBI Gene ID: 145873
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q0VG99
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mesoderm posterior bHLH transcription factor 2 interacts with:

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