NRG4, neuregulin 4

NRG4, neuregulin 4

• The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (HRG4, pro-neuregulin-4, membrane-bound isoform, heregulin 4, pro-NRG4,)
• NCBI Gene ID: 145957
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WWG1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

neuregulin 4 interacts with:

• CDGSH iron sulfur domain 2
  LHFPL tetraspan subfamily member 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.