DSG4, desmoglein 4

DSG4, desmoglein 4

• This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016]

• Gene Synonyms (CDGF13, CDHF13, HYPT6, LAH, desmoglein-4, cadherin family member 13,)
• NCBI Gene ID: 147409
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86SJ6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

desmoglein 4 interacts with:

• complexin 3
  lysophosphatidylcholine acyltransferase 4
  P2Y receptor family member 8
  pyrin and HIN domain family member 1
  shugoshin 2
  ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.