CDC42EP5, CDC42 effector protein 5

CDC42EP5, CDC42 effector protein 5

• Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]

• Gene Synonyms (Borg3, CEP5, cdc42 effector protein 5, CDC42 effector protein (Rho GTPase binding) 5, binder of Rho GTPases 3,)
• NCBI Gene ID: 148170
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6NZY7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CDC42 effector protein 5 interacts with:

• septin 7

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