RC3H1, ring finger and CCCH-type domains 1

RC3H1, ring finger and CCCH-type domains 1

• This gene encodes a protein containing RING-type and C3H1-type zinc finger motifs. The encoded protein recognizes and binds to a constitutive decay element (CDE) in the 3' UTR of mRNAs, leading to mRNA deadenylation and degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

• Gene Synonyms (RNF198, ROQUIN, roquin-1, RING finger and C3H zinc finger protein 1, RING finger and CCCH-type zinc finger domain-containing protein 1, RING finger protein 198, probable E3 ubiquitin-protein ligase Roquin,)
• NCBI Gene ID: 149041
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B9EGU6
  UNIPROT ID#>>B7ZMB3
  UNIPROT ID#>>Q5TC82
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ring finger and CCCH-type domains 1 interacts with:

• actin beta like 2
  ANKHD1-EIF4EBP3 readthrough
  ATP5MF-PTCD1 readthrough
  CCR4-NOT transcription complex subunit 6 like
  chromosome 11 open reading frame 98
  creatine kinase, mitochondrial 1A
  DEAH-box helicase 36
  DTW domain containing 2
  H2A clustered histone 19
  H2A clustered histone 21
  H3 clustered histone 13
  H4 clustered histone 15
  heterogeneous nuclear ribonucleoprotein U like 2
  lin-28 homolog B
  NOP9 nucleolar protein
  PAT1 homolog 1, processing body mRNA decay factor
  poly(A) specific ribonuclease subunit PAN3
  PPAN-P2RY11 readthrough
  ribosomal protein L22 like 1
  serum response factor binding protein 1
  tubulin beta class I
  zinc finger CCHC-type containing 24
  zinc finger protein 326

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.