- Gene Overview
- Interaction Network
- Sequence Verification
PUS10, pseudouridine synthase 10
-
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009]
-
Gene Synonyms (tRNA pseudouridine synthase Pus10, coiled-coil domain containing 139, coiled-coil domain-containing protein 139, pseudouridylate synthase 10, psi55 synthase, putative tRNA pseudouridine synthase Pus10, tRNA pseudouridine 55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase, CCDC139, DOBI, Hup10,)
- NCBI Gene ID:
150962
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>Q3MIT2
UNIPROT ID#>>A8K6R4
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
pseudouridine synthase 10 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|