Hmgb1, high mobility group box 1

Hmgb1, high mobility group box 1

• This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]

• (No alternate names found)
• NCBI Gene ID: 15289
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q58EV5
  UNIPROT ID#>>P63158
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

high mobility group box 1 interacts with:

• ataxin 1
  cytotoxic granule-associated RNA binding protein 1
  heat shock protein 8
  high mobility group box 2
  transcription factor E3
  transducin-like enhancer of split 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.