- Gene Overview
- Interaction Network
- Sequence Verification
ATP6V0E2, ATPase H+ transporting V0 subunit e2
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Multisubunit vacuolar-type proton pumps, or H(+)-ATPases, acidify various intracellular compartments, such as vacuoles, clathrin-coated and synaptic vesicles, endosomes, lysosomes, and chromaffin granules. H(+)-ATPases are also found in plasma membranes of specialized cells, where they play roles in urinary acidification, bone resorption, and sperm maturation. Multiple subunits form H(+)-ATPases, with proteins of the V1 class hydrolyzing ATP for energy to transport H+, and proteins of the V0 class forming an integral membrane domain through which H+ is transported. ATP6V0E2 encodes an isoform of the H(+)-ATPase V0 e subunit, an essential proton pump component (Blake-Palmer et al., 2007 [PubMed 17350184]).[supplied by OMIM, Mar 2008]
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Gene Synonyms (V-type proton ATPase subunit e 2, ATPase, H+ transporting V0 subunit E isoform 2-like, H+-ATPase e2 subunit, V-ATPase subunit e 2, lysosomal 9 kDa H(+)-transporting ATPase V0 subunit e2, vacuolar proton pump subunit e 2, vacuolar proton-ATPase subunit, ATP6V0E2L, C7orf32,)
- NCBI Gene ID:
155066
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>E9PAS2
UNIPROT ID#>>Q8NHE4
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
ATPase H+ transporting V0 subunit e2 interacts with:
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