SPRED1, sprouty related EVH1 domain containing 1

SPRED1, sprouty related EVH1 domain containing 1

• The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]

• Gene Synonyms (sprouty-related, EVH1 domain-containing protein 1, protein phosphatase 1, regulatory subunit 147, suppressor of Ras/MAPK activation, LGSS, NFLS, PPP1R147, hSpred1, spred-1,)
• NCBI Gene ID: 161742
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z699
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sprouty related EVH1 domain containing 1 interacts with:

• chromosome 2 open reading frame 68
  coiled-coil domain containing 185

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.