Prkaca, protein kinase, cAMP dependent, catalytic, alpha

Prkaca, protein kinase, cAMP dependent, catalytic, alpha

• This gene encodes a member of the serine/threonine protein kinase family. The holoenzyme, protein kinase A (also known as cyclic-AMP dependent protein kinase), mediates cellular response to changes in cyclic-AMP levels. This gene encodes the alpha catalytic subunit of protein kinase A. Protein kinase A-mediated signaling is transduced via phosphorylation of target proteins, and is important for many cellular functions, including mammalian sperm maturation and motility. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Apr 2013]

• (No alternate names found)
• NCBI Gene ID: 18747
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>P05132
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein kinase, cAMP dependent, catalytic, alpha interacts with:

• achaete-scute family bHLH transcription factor 4
  actin related protein 2/3 complex, subunit 1A
  ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
  ataxin 1
  calcium/calmodulin-dependent protein kinase kinase 2, beta
  CDK5 regulatory subunit associated protein 2
  cytotoxic granule-associated RNA binding protein 1
  DDB1 and CUL4 associated factor 7
  fibrous sheath CABYR binding protein
  FXYD domain-containing ion transport regulator 1
  glucokinase
  glucuronidase, beta
  glycogen synthase kinase 3 alpha
  GSK3B interacting protein
  inositol 1,4,5-trisphosphate 3-kinase A
  lymphocyte cytosolic protein 1
  patatin-like phospholipase domain containing 2
  protein kinase inhibitor, alpha
  protein kinase, cAMP dependent regulatory, type I beta
  protein kinase, cAMP dependent regulatory, type II beta
  protein phosphatase 1 catalytic subunit alpha
  protein phosphatase 1, regulatory inhibitor subunit 1B
  protein phosphatase 1, regulatory subunit 17
  protein phosphatase 2, regulatory subunit B', epsilon
  rosbin, round spermatid basic protein 1
  Rous sarcoma oncogene
  ryanodine receptor 2, cardiac
  solute carrier family 4 (anion exchanger), member 4
  SRY (sex determining region Y)-box 9
  TAO kinase 1
  TRAF2 and NCK interacting kinase
  transient receptor potential cation channel, subfamily V, member 1
  tyrosine hydroxylase
  USO1 vesicle docking factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.