SDR16C5, short chain dehydrogenase/reductase family 16C member 5

SDR16C5, short chain dehydrogenase/reductase family 16C member 5

• This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognizes all-trans-retinol and all-trans-retinaldehyde as substrates and exhibits a strong preference for NAD(+)/NADH as cofactors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (epidermal retinol dehydrogenase 2, epidermal retinal dehydrogenase 2, retinal short chain dehydrogenase reductase, retinal short-chain dehydrogenase reductase 2, EPHD-2, RDH#2, RDH-E2, RDHE2, retSDR2,)
• NCBI Gene ID: 195814
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KT84
  UNIPROT ID#>>G3V145
  UNIPROT ID#>>Q8N3Y7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

short chain dehydrogenase/reductase family 16C member 5 interacts with:

• heat shock transcription factor family, X-linked 1
  heat shock transcription factor family, X-linked 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.