TIGIT, T cell immunoreceptor with Ig and ITIM domains

TIGIT, T cell immunoreceptor with Ig and ITIM domains

• This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]

• Gene Synonyms (T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain containing 9, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain containing 3, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3, Washington University cell adhesion molecule, VSIG9, VSTM3, WUCAM,)
• NCBI Gene ID: 201633
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q495A1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

T cell immunoreceptor with Ig and ITIM domains interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.