TAPT1, transmembrane anterior posterior transformation 1

TAPT1, transmembrane anterior posterior transformation 1

• This gene encodes a highly conserved protein that localizes to the centrosome and/or ciliary basal body. Mutations in this gene disrupt Golgi morphology and trafficking and normal primary cilium formation and these mutations are congenitally manifested by severe undermineralization of the intra-uterine skeleton. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. In mouse, this gene is thought to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. [provided by RefSeq, Jan 2017]

• Gene Synonyms (transmembrane anterior posterior transformation protein 1 homolog, cytomegalovirus partial fusion receptor, CMVFR, OCLSBG,)
• NCBI Gene ID: 202018
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DJJ3
  UNIPROT ID#>>Q6NXT6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transmembrane anterior posterior transformation 1 interacts with:

• protein prenyltransferase alpha subunit repeat containing 1

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