Skip Navigation Links Home » Resources » Gene Detail

JMJD1C, jumonji domain containing 1C

Matching ORF Clones

    No catalog ORF clones available (link to the custom ORF request form)

Request a Custom Clone

Don't see what you need?

Request My Custom Clone »
  • Gene Overview
  • Interaction Network
  • Sequence Verification

JMJD1C, jumonji domain containing 1C

  • The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

  • Gene Synonyms (probable JmjC domain-containing histone demethylation protein 2C, TR-interacting protein 8, thyroid hormone receptor interactor 8, thyroid receptor-interacting protein 8, KDM3C, TRIP-8, TRIP8,)
  • NCBI Gene ID: 221037
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q15652
    UNIPROT ID#>>B7ZLC8
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

jumonji domain containing 1C interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.