MAST1, microtubule associated serine/threonine kinase 1

MAST1, microtubule associated serine/threonine kinase 1

• This gene is a member of the microtubule-associated serine/threonine kinase (MAST) family. The protein encoded by this gene has an N-terminal serine/threonine kinase domain followed by a postsynaptic density protein-95/discs large/zona occludens-1 (PDZ) domain. In mouse and rat, the orthologous protein associates with the cytoskeleton and can bind both beta-2-syntrophin and neuronal nitric oxide synthase (nNOS) through its PDZ domain. In mouse and rat, this protein also co-localizes with dystrophin- and utrophin-associated protein complexes (DAPC/UAPC) in the vascular endothelium of the central nervous system. [provided by RefSeq, May 2017]

• Gene Synonyms (MCCCHCM, SAST, microtubule-associated serine/threonine-protein kinase 1, syntrophin associated serine/threonine kinase, syntrophin-associated serine/threonine-protein kinase,)
• NCBI Gene ID: 22983
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y2H9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

microtubule associated serine/threonine kinase 1 interacts with:

• ECSIT signaling integrator
  exocyst complex component 6
  exosome component 1
  F-box and leucine rich repeat protein 12
  interferon induced protein with tetratricopeptide repeats 5
  lysyl oxidase like 4
  PML-RARA regulated adaptor molecule 1
  renalase, FAD dependent amine oxidase
  ring finger protein 32
  STAM binding protein like 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.