SIRT4, sirtuin 4

SIRT4, sirtuin 4

• This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]

• Gene Synonyms (NAD-dependent protein lipoamidase sirtuin-4, mitochondrial, NAD-dependent ADP-ribosyltransferase sirtuin-4, NAD-dependent protein deacetylase sirtuin-4, SIR2-like protein 4, regulatory protein SIR2 homolog 4, sir2-like 4, sirtuin type 4, SIR2L4,)
• NCBI Gene ID: 23409
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6E7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sirtuin 4 interacts with:

• sirtuin 3

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