RHOQ, ras homolog family member Q

RHOQ, ras homolog family member Q

• This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011]

• Gene Synonyms (rho-related GTP-binding protein RhoQ, RAS-like, family 7, member A, epididymis secretory protein Li 42, ras homolog gene family, member Q, ras-like protein TC10, ras-like protein family member 7A, ARHQ, HEL-S-42, RASL7A, TC10, TC10A,)
• NCBI Gene ID: 23433
• Species: Homo sapiens (Human)
• UNIPROT ID#>>D6W5A7
  UNIPROT ID#>>V9HWD0
  UNIPROT ID#>>P17081
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ras homolog family member Q interacts with:

• BTG3 associated nuclear protein
  CDC42 binding protein kinase gamma
  CDC42 effector protein 4
  dedicator of cytokinesis 8
  golgi associated PDZ and coiled-coil motif containing
  MORN repeat containing 4
  N-terminal glutamine amidase 1
  par-6 family cell polarity regulator alpha
  par-6 family cell polarity regulator beta
  zinc finger protein 417

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.