PDSS1, decaprenyl diphosphate synthase subunit 1

PDSS1, decaprenyl diphosphate synthase subunit 1

• The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency. [provided by RefSeq, Jul 2008]

• Gene Synonyms (decaprenyl-diphosphate synthase subunit 1, all-trans-decaprenyl-diphosphate synthase subunit 1, coenzyme Q1 homolog, decaprenyl pyrophosphate synthase subunit 1, polyprenyl pyrophosphate synthetase, prenyl (decaprenyl) diphosphate synthase, subunit 1, subunit 1 of decaprenyl diphosphate synthase, trans-prenyltransferase (TPT), trans-prenyltransferase 1, COQ1, COQ10D2, COQ1A, DPS, SPS, TPRT, TPT, TPT 1, hDPS1,)
• NCBI Gene ID: 23590
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5T2R2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

decaprenyl diphosphate synthase subunit 1 interacts with:

• acyl-CoA dehydrogenase family member 9
  La ribonucleoprotein 7, transcriptional regulator
  nectin cell adhesion molecule 4
  thioesterase superfamily member 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.