- Gene Overview
- Interaction Network
- Sequence Verification
ATP6V1C2, ATPase H+ transporting V1 subunit C2
-
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008]
-
Gene Synonyms (V-type proton ATPase subunit C 2, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2, V-ATPase C2 subunit, vacuolar proton pump subunit C 2, ATP6C2, VMA5,)
- NCBI Gene ID:
245973
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>Q8NEY4
UNIPROT ID#>>A0A0U1RR16
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
ATPase H+ transporting V1 subunit C2 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|