AKR7L, aldo-keto reductase family 7 like (gene/pseudogene)

AKR7L, aldo-keto reductase family 7 like (gene/pseudogene)

• This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a segregating pseudogene, where some individuals have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Feb 2017]

• Gene Synonyms (aflatoxin B1 aldehyde reductase member 4, AFB1 aldehyde reductase 3, aldo-keto reductase family 7 pseudogene, aldo-keto reductase family 7-like, aldoketoreductase 7-like, AFAR3, AFB1-AR 3, AFB1-AR3, AKR7A4,)
• NCBI Gene ID: 246181
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NHP1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

aldo-keto reductase family 7 like (gene/pseudogene) interacts with:

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