MMS22L, MMS22 like, DNA repair protein

MMS22L, MMS22 like, DNA repair protein

• The protein encoded by this gene forms a complex with tonsoku-like, DNA repair protein (TONSL), and this complex recognizes and repairs DNA double-strand breaks at sites of stalled or collapsed replication forks. The encoded protein also can bind with the histone-associated protein NFKBIL2 to help regulate the chromatin state at stalled replication forks. Finally, this gene appears to be overexpressed in most lung and esophageal cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]

• Gene Synonyms (protein MMS22-like, C6orf167, dJ39B17.2,)
• NCBI Gene ID: 253714
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6ZRQ5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MMS22 like, DNA repair protein interacts with:

• H2B clustered histone 1
  natural killer cell cytotoxicity receptor 3 ligand 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.