RASGRP3, RAS guanyl releasing protein 3

RASGRP3, RAS guanyl releasing protein 3

• The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]

• Gene Synonyms (ras guanyl-releasing protein 3, CalDAG-GEFIII, RAS guanyl releasing protein 3 (calcium and DAG-regulated), calcium and DAG-regulated guanine nucleotide exchange factor III, calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III, guanine nucleotide exchange factor for Rap1, GRP3,)
• NCBI Gene ID: 25780
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IV61
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RAS guanyl releasing protein 3 interacts with:

• dynein light chain LC8-type 2
  hydroxysteroid 17-beta dehydrogenase 11

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.