GALNT3, polypeptide N-acetylgalactosaminyltransferase 3

GALNT3, polypeptide N-acetylgalactosaminyltransferase 3

• This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities. [provided by RefSeq, Jul 2008]

• Gene Synonyms (GalNAc-T3, HFTC, HFTC1, HHS, polypeptide N-acetylgalactosaminyltransferase 3, GalNAc transferase 3, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3), polypeptide GalNAc transferase 3, polypeptide GalNAc-transferase T3, pp-GaNTase 3, protein-UDP acetylgalactosaminyltransferase 3,)
• NCBI Gene ID: 2591
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14435
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

polypeptide N-acetylgalactosaminyltransferase 3 interacts with:

• amyloid beta precursor protein binding protein 2
  mitogen-activated protein kinase 8 interacting protein 2
  ring finger and SPRY domain containing 1
  solute carrier family 15 member 3
  unc-93 homolog B1, TLR signaling regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.