ASPM, assembly factor for spindle microtubules

ASPM, assembly factor for spindle microtubules

• This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]

• Gene Synonyms (abnormal spindle-like microcephaly-associated protein, abnormal spindle microtubule assembly, asp (abnormal spindle) homolog, microcephaly associated, ASP, Calmbp1, MCPH5,)
• NCBI Gene ID: 259266
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KWI2
  UNIPROT ID#>>Q8IZT6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

assembly factor for spindle microtubules interacts with:

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