EGFL6, EGF like domain multiple 6

EGFL6, EGF like domain multiple 6

• This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]

• Gene Synonyms (epidermal growth factor-like protein 6, EGF repeat-containing protein 6, EGF-like protein 6, MAM and EGF domain containing, MAM and EGF domains-containing gene protein, MAEG, W80,)
• NCBI Gene ID: 25975
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IUX8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EGF like domain multiple 6 interacts with:

• ALG13 UDP-N-acetylglucosaminyltransferase subunit
  coiled-coil domain containing 85C
  family with sequence similarity 8 member A1
  HECT domain E3 ubiquitin protein ligase 3
  LDL receptor related protein 1B
  synoviolin 1
  ubiquilin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.